- TLE1 / TLE 1 Recombinant Monoclonal Antibody
- LSBio
- Pricing InfoSupplier PageView Company Product Page
- LS-B16303
- TLE1/2946R
- aa 175-338
- ESG, ESG1, GRG1, TLE-1
- Human
- IHC-P
- TLE1 / TLE 1
- Rabbit
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Recombinant Monoclonal
- TLE family member 1, transcriptional corepressor
- Protein A/G purified
- Unconjugated
- IgG
- 100 µg
Specifications/Features
Specificity: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies